Seven top picks — ranked by authentic reviews, current price, enzymatic formula, and for dogs.
Some links are affiliate links. We may earn a small commission at no extra cost to you. How we make money.
All picks, best reviews first.
Virbac C.E.T. is widely regarded by veterinarians as the gold standard for daily dog dental care thanks to its clinically proven dual-enzyme system. It effectively prevents plaque buildup while offering flavors pets love.
Matches for dogs · dental care · enzymatic formula
Price range
$12.29–$17.99
Sorted by overall review score — not by sponsorship.
Sentry Petrodex offers a powerful non-foaming enzymatic formula in a generous tube size that gives great value. Its strong poultry flavor makes routine brushing easier for reluctant pets.
Matches for dogs · dental care · enzymatic formula
Best price
$18.99
Petsmile is one of the very few toothpastes accepted by the Veterinary Oral Health Council (VOHC) for plaque inhibition. Its proprietary Calprox formula works effectively with or without vigorous brushing.
Matches for dogs · dental care · enzymatic formula
Best price
$104.99
Vetoquinol Enzadent utilizes a specialized triple-enzyme complex that actively polishes teeth and curbs harmful oral bacteria. Dogs enjoy the appetizing poultry flavor, making the brushing routine hassle-free.
Matches for dogs · dental care · enzymatic formula
Best price
$20.41
Vet's Best combines natural ingredients like aloe and neem oil with active enzymes to fight tartar and freshen breath gently. It is an affordable and widely trusted choice for regular dental care.
Matches for dogs · dental care · enzymatic formula
Price range
$5.99–$11.99
Nylabone Advanced Oral Care features their proprietary Denta-C blend alongside enzymes to diminish plaque harboring bacteria. It provides an approachable and effective solution for everyday oral hygiene.
Matches for dogs · dental care · enzymatic formula
Price range
$6.99–$9.99
RADIUS Canine Dental Gel relies on organic coconut oil and natural botanical extracts rather than synthetic components to freshen breath and clean teeth. It is an ideal organic dental choice for eco-conscious dog owners.
Matches for dogs · dental care
Price range
$11.88–$14.99
All picks, cheapest first.
Vet's Best combines natural ingredients like aloe and neem oil with active enzymes to fight tartar and freshen breath gently. It is an affordable and widely trusted choice for regular dental care.
Matches for dogs · dental care · enzymatic formula
Price range
$5.99–$11.99
Sorted by price — not by sponsorship.
Nylabone Advanced Oral Care features their proprietary Denta-C blend alongside enzymes to diminish plaque harboring bacteria. It provides an approachable and effective solution for everyday oral hygiene.
Matches for dogs · dental care · enzymatic formula
Price range
$6.99–$9.99
RADIUS Canine Dental Gel relies on organic coconut oil and natural botanical extracts rather than synthetic components to freshen breath and clean teeth. It is an ideal organic dental choice for eco-conscious dog owners.
Matches for dogs · dental care
Price range
$11.88–$14.99
Virbac C.E.T. is widely regarded by veterinarians as the gold standard for daily dog dental care thanks to its clinically proven dual-enzyme system. It effectively prevents plaque buildup while offering flavors pets love.
Matches for dogs · dental care · enzymatic formula
Price range
$12.29–$17.99
Sentry Petrodex offers a powerful non-foaming enzymatic formula in a generous tube size that gives great value. Its strong poultry flavor makes routine brushing easier for reluctant pets.
Matches for dogs · dental care · enzymatic formula
Best price
$18.99
Vetoquinol Enzadent utilizes a specialized triple-enzyme complex that actively polishes teeth and curbs harmful oral bacteria. Dogs enjoy the appetizing poultry flavor, making the brushing routine hassle-free.
Matches for dogs · dental care · enzymatic formula
Best price
$20.41
Petsmile is one of the very few toothpastes accepted by the Veterinary Oral Health Council (VOHC) for plaque inhibition. Its proprietary Calprox formula works effectively with or without vigorous brushing.
Matches for dogs · dental care · enzymatic formula
Best price
$104.99
Everything you need to know before choosing.
Virbac C.E.T. Enzymatic Toothpaste (scores 9.3/10). Virbac C.E.T. is widely regarded by veterinarians as the gold standard for daily dog dental care thanks to its clinically proven dual-enzyme system. It effectively prevents plaque buildup while offering flavors pets love.
Virbac C.E.T. Enzymatic Toothpaste is the top pick for enzymatic formula.
Virbac C.E.T. Enzymatic Toothpaste is the top pick for for dogs.
Virbac C.E.T. Enzymatic Toothpaste is the top pick for dental care.
