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Best Dog Enzymatic Toothpaste

Ten top picks — ranked by authentic reviews, current price, enzymatic formula, and for dogs.

Some links are affiliate links. We may earn a small commission at no extra cost to you. How we make money.

Top Rated

All picks, best reviews first.

Petrodex Enzymatic Toothpaste for Dogs
Best Pick

Petrodex Enzymatic Toothpaste for Dogs

Petrodex Enzymatic Toothpaste uses hydrogen peroxide-producing enzymes to effectively break down plaque and tartar while providing a palatable poultry flavor dogs love.

Highly appealing flavorEffective plaque controlGreatly improves breath9.2

Matches for dogs · dental care · enzymatic formula

Best price

$4.99

View pricesFull analysis

More dog enzymatic toothpaste

Sorted by overall review score — not by sponsorship.

Sentry Petrodex Enzymatic Toothpaste for Dogs

Sentry Petrodex Enzymatic Toothpaste for Dogs

Sentry Petrodex uses a specialized enzymatic action to help prevent the accumulation of tartar and plaque while offering a taste dogs enjoy.

Highly appealing flavorEffective plaque controlGreatly improves breath9.2

Matches for dogs · dental care · enzymatic formula

Best price

$4.99

View pricesFull analysis
Virbac CET Enzymatic Toothpaste

Virbac CET Enzymatic Toothpaste

Virbac C.E.T. is a veterinary-grade enzymatic toothpaste designed to inhibit plaque formation and freshen breath with a highly palatable, dual-enzyme formula.

Vet recommendedPlaque buildup minimizedPets love taste8.8

Matches for dogs · dental care · enzymatic formula

Best price

$11.52

View pricesFull analysis
Nylabone Advanced Oral Care Enzymatic Toothpaste

Nylabone Advanced Oral Care Enzymatic Toothpaste

Nylabone Advanced Oral Care features Denta-C scientifically formulated enzymes to help reduce plaque and bacteria buildup on canine teeth.

Affordable pricingReduces plaque buildupImproves bad breath7.8

Matches for dogs · dental care · enzymatic formula

Best price

$6.50

View pricesFull analysis
TropiClean Fresh Breath Clean Teeth Dental Health Gel

TropiClean Fresh Breath Clean Teeth Dental Health Gel

TropiClean Fresh Breath Gel utilizes naturally derived enzymes to destroy plaque and tartar without requiring brushing, making dental care simple.

Effective tartar removalNo brushing requiredSafe ingredients profile6.8

Matches for dogs · dental care · enzymatic formula

Best price

$12.99

View pricesFull analysis
Vet's Best Enzymatic Dog Toothpaste

Vet's Best Enzymatic Dog Toothpaste

Vet's Best Enzymatic Toothpaste combines natural enzymes, baking soda, and neem oil to fight tartar and plaque while soothing gums and freshening breath.

Affordable price pointEnzymatic cleaning actionFreshens bad breath6.2

Matches for dogs · dental care · enzymatic formula

Best price

$11.99

View pricesFull analysis
Pets Smile Say Cheese Enzymatic Toothpaste

Pets Smile Say Cheese Enzymatic Toothpaste

Petsmile features Calvrox and natural enzymes backed by VOHC approval to safely dissolve plaque and keep teeth clean without mandatory brushing.

VOHC approved certificationEnzymatic dental care5.2

Matches for dogs · dental care · enzymatic formula

Best price

$24.99

View pricesFull analysis
Burt's Bees for Dogs Beeswax Enzymatic Toothpaste

Burt's Bees for Dogs Beeswax Enzymatic Toothpaste

Burt's Bees for Dogs harnesses natural beeswax and enzymes to gently scrub away plaque, supporting overall canine oral health naturally.

Natural brand reputation5.0

Matches for dogs · dental care · enzymatic formula

Best price

$10.99

View pricesFull analysis
Arm & Hammer Treadz Enzymatic Toothpaste for Dogs

Arm & Hammer Treadz Enzymatic Toothpaste for Dogs

Arm & Hammer Treadz uses natural baking soda and enzymes to break down buildup on teeth and gums while neutralizing bad breath odor.

Baking soda poweredAffordable daily optionTargeted tartar control

Matches for dogs · dental care · enzymatic formula

Best price

$6.10

View pricesFull analysis
Vetoquinol Zymox Oratene Brushless Enzymatic Oral Gel

Vetoquinol Zymox Oratene Brushless Enzymatic Oral Gel

Vetoquinol Zymox Oratene utilizes a patented LP3 enzyme system to clear plaque and soothe dry oral tissues without requiring manual brushing.

Brushless gel applicationLP3 enzyme systemSoothes severe dryness

Matches for dogs · dental care · enzymatic formula

Best price

$14.99

View pricesFull analysis

Lowest Price

All picks, cheapest first.

Petrodex Enzymatic Toothpaste for Dogs

Petrodex Enzymatic Toothpaste for Dogs

Petrodex Enzymatic Toothpaste uses hydrogen peroxide-producing enzymes to effectively break down plaque and tartar while providing a palatable poultry flavor dogs love.

Highly appealing flavorEffective plaque controlGreatly improves breath9.2

Matches for dogs · dental care · enzymatic formula

Best price

$4.99

View pricesFull analysis

More dog enzymatic toothpaste

Sorted by price — not by sponsorship.

Sentry Petrodex Enzymatic Toothpaste for Dogs

Sentry Petrodex Enzymatic Toothpaste for Dogs

Sentry Petrodex uses a specialized enzymatic action to help prevent the accumulation of tartar and plaque while offering a taste dogs enjoy.

Highly appealing flavorEffective plaque controlGreatly improves breath9.2

Matches for dogs · dental care · enzymatic formula

Best price

$4.99

View pricesFull analysis
Arm & Hammer Treadz Enzymatic Toothpaste for Dogs

Arm & Hammer Treadz Enzymatic Toothpaste for Dogs

Arm & Hammer Treadz uses natural baking soda and enzymes to break down buildup on teeth and gums while neutralizing bad breath odor.

Baking soda poweredAffordable daily optionTargeted tartar control

Matches for dogs · dental care · enzymatic formula

Best price

$6.10

View pricesFull analysis
Nylabone Advanced Oral Care Enzymatic Toothpaste

Nylabone Advanced Oral Care Enzymatic Toothpaste

Nylabone Advanced Oral Care features Denta-C scientifically formulated enzymes to help reduce plaque and bacteria buildup on canine teeth.

Affordable pricingReduces plaque buildupImproves bad breath7.8

Matches for dogs · dental care · enzymatic formula

Best price

$6.50

View pricesFull analysis
Burt's Bees for Dogs Beeswax Enzymatic Toothpaste

Burt's Bees for Dogs Beeswax Enzymatic Toothpaste

Burt's Bees for Dogs harnesses natural beeswax and enzymes to gently scrub away plaque, supporting overall canine oral health naturally.

Natural brand reputation5.0

Matches for dogs · dental care · enzymatic formula

Best price

$10.99

View pricesFull analysis
Virbac CET Enzymatic Toothpaste

Virbac CET Enzymatic Toothpaste

Virbac C.E.T. is a veterinary-grade enzymatic toothpaste designed to inhibit plaque formation and freshen breath with a highly palatable, dual-enzyme formula.

Vet recommendedPlaque buildup minimizedPets love taste8.8

Matches for dogs · dental care · enzymatic formula

Best price

$11.52

View pricesFull analysis
Vet's Best Enzymatic Dog Toothpaste

Vet's Best Enzymatic Dog Toothpaste

Vet's Best Enzymatic Toothpaste combines natural enzymes, baking soda, and neem oil to fight tartar and plaque while soothing gums and freshening breath.

Affordable price pointEnzymatic cleaning actionFreshens bad breath6.2

Matches for dogs · dental care · enzymatic formula

Best price

$11.99

View pricesFull analysis
TropiClean Fresh Breath Clean Teeth Dental Health Gel

TropiClean Fresh Breath Clean Teeth Dental Health Gel

TropiClean Fresh Breath Gel utilizes naturally derived enzymes to destroy plaque and tartar without requiring brushing, making dental care simple.

Effective tartar removalNo brushing requiredSafe ingredients profile6.8

Matches for dogs · dental care · enzymatic formula

Best price

$12.99

View pricesFull analysis
Vetoquinol Zymox Oratene Brushless Enzymatic Oral Gel

Vetoquinol Zymox Oratene Brushless Enzymatic Oral Gel

Vetoquinol Zymox Oratene utilizes a patented LP3 enzyme system to clear plaque and soothe dry oral tissues without requiring manual brushing.

Brushless gel applicationLP3 enzyme systemSoothes severe dryness

Matches for dogs · dental care · enzymatic formula

Best price

$14.99

View pricesFull analysis
Pets Smile Say Cheese Enzymatic Toothpaste

Pets Smile Say Cheese Enzymatic Toothpaste

Petsmile features Calvrox and natural enzymes backed by VOHC approval to safely dissolve plaque and keep teeth clean without mandatory brushing.

VOHC approved certificationEnzymatic dental care5.2

Matches for dogs · dental care · enzymatic formula

Best price

$24.99

View pricesFull analysis

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Frequently asked questions

Everything you need to know before choosing.

01

What is the best Dog Enzymatic Toothpaste?

Petrodex Enzymatic Toothpaste for Dogs (scores 9.2/10). Petrodex Enzymatic Toothpaste uses hydrogen peroxide-producing enzymes to effectively break down plaque and tartar while providing a palatable poultry flavor dogs love.

02

Which Dog Enzymatic Toothpaste is best for enzymatic formula?

Petrodex Enzymatic Toothpaste for Dogs is the top pick for enzymatic formula.

03

Which Dog Enzymatic Toothpaste is best for for dogs?

Petrodex Enzymatic Toothpaste for Dogs is the top pick for for dogs.

04

Which Dog Enzymatic Toothpaste is best for dental care?

Petrodex Enzymatic Toothpaste for Dogs is the top pick for dental care.

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